Swine flu vaccine 'step closer'

Read and answer:

1. Where are the scientists from?
2. Is it important for manufacturers to start large-scale production of a virus against the H1N1 strain?
3. Name one of the labs working towards a vaccine.
4. What do scientists have to create to get a strain suitable for vaccine manufacture?
5. What is the name of the technique used?

Swine flu vaccine 'step closer'

Influenza vaccines can be manufactured on a large scale
A viral strain which can be used to make a vaccine against swine flu has been produced by UK scientists.
It is a "crucial step" for manufacturers to start large-scale production of a virus against the H1N1 strain, they said.
The National Institute for Biological Standards and Control is one of a handful of laboratories globally working towards a vaccine.
US researchers also recently produced a candidate "starting strain".
To get a strain suitable for vaccine manufacture, scientists have to create a hybrid virus which is a cross between the H1N1 virus which is causing disease and "a tried and tested laboratory strain".
Using a technique called reverse genetics the researchers took gene sequences encoding parts of the swine flu virus that are recognised by the body's immune system and combined them with gene sequences from laboratory strains.

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